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You must take Boniva exactly as directed or you will lower the amount of medicine you absorb into your body or you may cause yourself harm. 50mg is a once-a-month supply. Take your dose by mouth first thing in the morning, after you are up for the day. Do not eat or drink anything before you take Boniva. Swallow the tablet with a full glass (6 to 8 ounces) of plain water. Do not take Boniva with any other drink. Do not chew or crush the tablet. After taking Boniva, do not eat breakfast, drink, or take any other medicines or vitamins for at least 1 hour. Stand or sit up for at least 1 hour after taking Boniva; do not lie down. Do not take your medicine more often than directed.

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