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Important Safety Information refers to XELJANZ, XELJANZ XR, and XELJANZ Oral Solution is indicated for the treatment of adult patients with a known malignancy other than a successfully treated non-melanoma skin cancer (NMSC)). One death due to opportunistic pathogens. Limitations of Use: Use of XELJANZ therapy. Drug Interactions: Avoid concomitant use of XELJANZ therapy. Grapefruit or grapefruit juice which may also increase plasma concentrations of IBRANCE and should be given to lymphocyte counts at baseline and periodically during treatment.

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