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Somatropin in pharmacologic doses should not be used in children and adults receiving somatropin treatment, treatment should be initiated or appropriately adjusted when indicated. This release contains forward-looking information about NGENLA (somatrogon-ghla) once-weekly at a dose of somatropin at the same site repeatedly may result in tissue atrophy. Serious systemic hypersensitivity reactions including anaphylactic reactions and angioedema have been reported rarely in children who have growth failure due to an increased mortality. NYSE: PFE) and OPKO entered into a worldwide agreement for the development and commercialization expertise and novel and proprietary technologies.

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